About Defy of Indiana

Our Mission

At Defy, we are on a mission to provide our patients with comprehensive, personalized and holistic care that empowers them to achieve their highest standards of well-being.

We are here to help you defy the odds and achieve all your health goals.

It all starts with simply knowing that feeling better IS possible!

Our Philosophy of Care

The body is a complex system, made up of several interconnected parts that play a vital role in overall health. Disease is often caused by an imbalance in the body’s systems.


At Defy, we don’t believe in band-aid fixes. We help restore balance to the body’s systems by addressing the root cause of your health concerns through deeply personalized, expert care.

Our Commitment to You

Everyone has the potential to lead a vibrant, healthy and fulfilling life. At Defy, we strive to make this potential a reality.

We are committed to providing the highest quality of care through:

Meet Our Team

Mara Wattam

MSN, FNP

Mara Wattam

MSN, FNP

Mara has enjoyed a career in healthcare with a variety of experience spanning 20 years. Her focus over the recent years has been in functional medicine, providing care that heals the root cause, rather than treating symptoms. She brings to Defy her functional medicine expertise and relevant knowledge and skills in treating gut health, administering peptide therapies, bioidentical hormone replacement therapy as well as weight loss management.

Mara Wattam

MSN, FNP

Mara Wattam

MSN, FNP

Mara has enjoyed a career in healthcare with a variety of experience spanning 20 years. Her focus over the recent years has been in functional medicine, providing care that heals the root cause, rather than treating symptoms. She brings to Defy her functional medicine expertise and relevant knowledge and skills in treating gut health, administering peptide therapies, bioidentical hormone replacement therapy as well as weight loss management.

Dr. Tina Harrison

Medical Director

Dr. Tina Harrison

Medical Director

A Board Certified Internal Medicine physician, Tina brings 20+ years of experience in treating acute and chronic illnesses. Tina has served as the medical director and liaison for several hospital networks and individual medical practices. At Defy, she brings her expertise of integrating functional and traditional medicine, to enhance health for all.

Dr. Amy Marckese

Founder/Owner

Dr. Amy Marckese

Founder/ Owner

Dr. Amy Marckese is the owner of DentalSpa, a leading general and cosmetic dental office in Indianapolis. Over the last two decades, she has built a practice focusing on customer service and patient experience. Almost three years ago, she was “sick and tired of feeling sick and tired.” She went to multiple doctors who told her, “this is just part of going through menopause.” She was tired all of the time, cried a lot, was in a horrible mood, had no sex drive and was 100 pounds overweight — on the verge of being diabetic. She was simply no longer the person she used to be inside or out. Over the last two and half years, Amy has experienced firsthand the transformative benefits of hormone balancing, peptide therapy and exercise. Her journey has led her to looking and most importantly FEELING better than she did 10 years ago! Her desire to share her experiential wisdom led her to wanting to open DEFY of INDIANA to help others look and feel they way they want to look and feel.

Dr. Amy Marckese

Founder/Owner

Dr. Amy Marckese

Founder/ Owner

Dr. Amy Marckese is the owner of DentalSpa, a leading general and cosmetic dental office in Indianapolis. Over the last two decades, she has built a practice focusing on customer service and patient experience. Almost three years ago, she was “sick and tired of feeling sick and tired.” She went to multiple doctors who told her, “this is just part of going through menopause.” She was tired all of the time, cried a lot, was in a horrible mood, had no sex drive and was 100 pounds overweight — on the verge of being diabetic. She was simply no longer the person she used to be inside or out. Over the last two and half years, Amy has experienced firsthand the transformative benefits of hormone balancing, peptide therapy and exercise. Her journey has led her to looking and most importantly FEELING better than she did 10 years ago! Her desire to share her experiential wisdom led her to wanting to open DEFY of INDIANA to help others look and feel they way they want to look and feel.

Leanne Wheeldon

Licensed Esthetician

Leanne Wheeldon

Licensed Esthetician

Leanne is excited to help you along your skincare journey in reversing sun damage and slowing down aging. Her goal is to help you recognize that many skin conditions can be prevented, controlled, and treated with awareness and the right measures. She prides herself in helping your skin get the nourishment it deserves while providing you with a relaxing environment to indulge in self-care and help you attain healthy skin again.

At Defy, we offer a variety of services to help you upgrade your health and overall well-being. Defy is WHERE FEELING BETTER BEGINS!

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